Citrus is the most Dice important fruit crop in Brazil and Citrus tristeza virus (CTV) is considered one of the most important pathogens of citrus.Most citrus species and varieties are susceptible to CTV infection.However, Poncirus trifoliata, a close relative of citrus, is resistant to the virus.In order to better understand the responses of citru
Abstract Background Human microRNAs (miRNAs) have diverse functions in biology, and play a role in nearly every biological process.Here we report that miR-520d-5p (520d-5p) causes undifferentiated cancer cells to adopt benign or normal status in vivo in immunodeficient mice via demethylation and P53 upregulation.Further we found that 520-5p causes
Abstract Drug-resistant bacterial biofilm infections (BBIs) are refractory to elimination.Near-infrared-II photothermal therapy (NIR-II PTT) and chemodynamic therapy (CDT) are emerging antibiofilm approaches because of the heavy damage they inflict upon bacterial membrane structures and minimal drug-resistance.Hence, synergistic NIR-II PTT and CDT
Comprehensive characterization of metabolites and metabolic profiles in plasma has considerable significance in determining the efficacy and safety of traditional Chinese medicine (TCM) in Screens vivo.However, this process is usually hindered by the insufficient characteristic fragments of metabolites, ubiquitous matrix interference, and complicat